Parkinson Disease పార్కిన్‌సన్స్ డిసీజ్

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Parkinson Disease పార్కిన్‌సన్స్ డిసీజ్…. మన శరీరం చేసే ప్రతి పనిని నియంత్రించే నరాలు మన మెదడులో ఒక్కో కేంద్రంలో ఉంటాయి. అదేవిధంగా మన కదిలికలను నియంత్రించడానికి కూడా కొన్ని కణాలుంటాయి. ఇవి కదలికలకు అవసరమయ్యే డోపమైన్(dopamine) అనే రసాయనాన్ని ఉత్పత్తి చేస్తాయి.

ఈ కణాలు కొందరిలో డీజనరేట్ అవుతాయి. ఇవి నశించడం వల్ల అవి ఉత్పత్తి చేసే డోపమైన్ కూడా తగ్గిపోతుంది. దాంతో కదలికలు ప్రభావితమై సక్రమంగా కాళ్లూ, చేతులు కదల్చడంలో ఇబ్బందులు ఎదురవుతాయి. కాళ్లూ చేతుల్లో వణుకు ఉంటుంది. దీన్నే పార్కిన్‌సన్స్ వ్యాధిగా పరిగణిస్తారు. సాధారణంగా పార్కిన్‌సన్స్ వ్యాధి మధ్యవయసువాళ్లలో 40-50 ఏళ్ల వాళ్లలో ఎక్కువగా కనిపిస్తుంది. దీనికి జన్యుకారణాలేమీ లేవు. ఇది వంశపారంపర్యంగా రాదు.

Parkinson Disease పార్కిన్‌సన్స్ డిసీజ్
Woman hand holding old senior elder hand with love and care

Parkinson Disease పార్కిన్‌సన్స్ డిసీజ్ 

ఎలా గుర్తిస్తారు?

అకేనేషియా(akinesia) అంటే కదల్చలేకపోతారు. మూవ్‌మెంట్ చాలా నెమ్మదిగా ఉంటుంది (బ్రాడి కైనేషియా)(bradykinesia). ముందు ఒక వైపు కాలు, చెయ్యి ప్రభావితం అయ్యాక రెండో వైపు భాగం ప్రభావితం అవుతుంది.

అంటే ఒకవైపు కాళ్లూ, చేతులు వణకడం, కదల్చలేకపోవడం వంటి సమస్యలుంటాయన్నమాట. నడవడం, చేతులను కదిలించడం చేయలేరు.

ముఖంలోని కండరాలను కూడా కదల్చలేరు. దాంతో ముఖం భావోద్వేగాలను ఎక్స్‌ప్రెస్ చేయలేనిదిగా అవుతుంది. మాట నిదానం అవుతుంది. మాట శబ్దం తగ్గిపోతుంది. చిన్నగా, మెల్లగా మాట్లాడుతారు. మాట తడబడుతుంది.

అయితే కాగ్నిటివ్ సామర్థ్యం మాత్రం బాగానే ఉంటుంది. అంటే ఆలోచనా శక్తి, నిర్ణయాత్మక శక్తి, ఏకాగ్రత, ప్రవర్తన మాత్రం బాగానే ఉంటాయి. కాగ్నిటివ్ సామర్థ్యాలు దెబ్బతినడానికి ఓ పదిహేనేళ్లు పట్టొచ్చు.

డయాగ్నసిస్ :

నెమ్మదిగా కదిలించడం, స్టిఫ్‌నెస్, వణకడం.. ఈ మూడు లక్షణాలూ ఒకవైపు మొదలై తరువాత రెండో వైపు రావడం పార్కిన్‌సన్స్ వ్యాధి నిర్దుష్ట లక్షణం.

దీని ఆధారంగానే క్లినికల్ పరీక్షల ద్వారానే వ్యాధిని తెలుసుకుంటారు. ఎంఆర్‌ఐ లాంటివి అవసరం లేదు.

అయితే ప్రోగ్రెసివ్ సుప్రా న్యూక్లియర్ పాల్సీ, మల్టీ సిస్టమ్ అట్రోపీ లాంటి ఇతర డీజనరేటివ్ వ్యాధులుంటే కూడా వీటిలో మూడింటిలో ఏదో ఒకటి లేదా రెండు లక్షణాలైనా రావొచ్చు. దీన్ని పార్కిన్‌సోనిజమ్ అంటారు.

పార్కిన్‌సోనిజమ్ ఉన్నప్పుడు అంటే కేవలం నడవడంలో ఇబ్బంది లేదా వణకడం మాత్రమే ఉండి, కాగ్నిషన్ దెబ్బతినకుండా ఉంటే ఇతర డీజనరేటివ్ వ్యాధులకు సిటి స్కాన్, ఎంఆర్‌ఐ లాంటి పరీక్షలు అవసరమవుతాయి.

గత అల్లోపతి చికిత్స:

మెదడులో కదలికలకు సంబంధించిన నరాలు డీజనరేట్ అయినప్పుడు ఆ డీనజనరేటివ్ కణాలను కంట్రోల్ చేసే ఇతర నాడీకణాలు ఎక్కువ పనిచేస్తాయి. అందువల్ల వణకడం, స్టిఫ్‌నెస్ లాంటి ఇబ్బందులు వస్తాయి.

అయితే డీజనరేటివ్ కణాలను కంట్రోల్ చేసే నాడీకణాలను చంపేస్తే తాత్కాలికంగా ఈ సమస్యలు తగ్గుతాయి.

అందుకే ఈ పార్కిన్‌సన్స్ జబ్బు ఉన్నప్పుడు ఎక్కువగా పనిచేసే నరాలకు లోపల ఆల్కహాల్ ఇంజెక్షన్ ఇచ్చి ఆ నరాలను చనిపోయేలా చేసేవాళ్లు. దీన్ని లీషనింగ్ అంటారు.

ఇందుకోసం రేడియో ఫ్రీక్వెన్సీ అబ్లేషన్(radiofrequency ablation) కూడా చేస్తారు. పుర్రె మీద చిన్న రంధ్రం చేసి, ఇంజెక్షన్ ద్వారా ఈ ట్రీట్‌మెంట్ చేసేవాళ్లు.

అల్లోపతి సైడ్ ఎఫెక్టులిచ్చే మందులు:

ఆ తర్వాత మెడికల్ ట్రీట్‌మెంట్ అందుబాటులోకి వచ్చింది. ఈ చికిత్సలో భాగంగా తగ్గిపోయిన డోపమైన్ రసాయనాన్ని టాబ్లెట్ రూపంలో ఇవ్వడం మొదలైంది.

కదలికలను కంట్రోల్ చేసే నరాలు పనిచేయడానికి ఈ డోపమైన్ కావాలి. అందువల్ల డోపమైన్ మందులు వేసుకుంటే ఉపశమనం కలుగుతుంది.

అయితే ఈ టాబ్లెట్ల వల్ల అనేక సైడ్ ఎఫెక్టులుంటాయి. లక్షణాలు అప్పుడప్పుడే మొదలైన వాళ్లకు, అంటే కొత్తగా వ్యాధి మొదలైన వాళ్లకు డోపమైన్ ఇస్తే అది బాగానే పనిచేస్తుంది.

కాని డీజనరేటివ్ ప్రాసెస్ ఆగదు. కదలికలను కంట్రోల్ చేసే నరాలు ఇంకా డీజనరేట్ అవుతూనే ఉంటాయి. ఎక్కువ కణాలు డీజనరేట్ అవుతున్న కొద్దీ ఎక్కువ డోపమైన్ డోస్ తీసుకోవాల్సి ఉంటుంది.

దాంతో అదనపు డోపమైన్ మెదడు కణాలపై ప్రభావం చూపించి, కదలికలను కూడా వేగవంతం చేస్తుంది. అంతే ఈ ప్రభావం వల్ల కాళ్లూ చేతులను ఆపకుండా కదిలిస్తూనే ఉంటారు.

ఒకరకంగా చెప్పాలంటే డ్యాన్స్ చేస్తున్నట్టు ఉంటారు. దీన్ని డిస్కైనీసియా(dyskinesia) అంటారు. టాబ్లెట్ వేసుకున్న కొన్ని గంటల వరకు ఇలా ఉంటుంది. మందు ప్రభావం తగ్గిన తరువాత మళ్లీ మామూలైపోతారు. కానీ ఆ తరువాత ఫ్రీజ్ అయిపోతారు.

అన్నీ స్టిఫ్ అయిపోతాయి. అందువల్ల చాలామంది ఈ డిస్కైనీసియా స్టేట్‌లో ఉండడమే బెటర్ అనుకుంటారు. కాని ఇది పూర్తి ఉపశమనం కలిగించదు.

అల్లోపతి సర్జరీ డిబిఎస్ :

మందుల వల్ల సమస్యలు ఎక్కువ కాబట్టి దీనికి ప్రత్యామ్నయంగా పార్కిన్‌సన్స్ వ్యాధికి కూడా సర్జరీ చేస్తున్నారు. దీన్నే డీప్ బ్రెయిన్ స్టిమ్యులేషన్ సర్జరీ -డిబిఎస్ సర్జరీ అంటారు.

ఈ విధానంలో ఆల్కహాల్ ఇంజెక్షన్ ఇవ్వడానికి బదులుగా కరెంట్ పంపిస్తారు. ఎక్కువ పని చేసే నరానికి ఈ కరెంట్ పంపిస్తారు. దాంతో లక్షణాలు తగ్గుముఖం పడతాయి.

కరెంట్ ఆపితే మళ్లీ పనిచేస్తాయి. గుండెకు పేస్‌మేకర్ లాగానే ఇది బ్రెయిన్ పేస్‌మేకర్. బ్యాటరీని కాలర్ బోన్ కింద చర్మం లోపల అమరుస్తారు. దీని కనెక్టింగ్ వైర్‌ని పుర్రెకు డ్రిల్ చేసి నరానికి స్టీరియోటాక్టిక్ టెక్నాలజీ ద్వారా పంపిస్తారు.

రిమోట్ లాగా ఉండే ఒక యూనిట్‌తో కరెంట్‌ని ఆన్, లేదా ఆఫ్ చేయొచ్చు. ఇది పేషెంటు మెలకువతో ఉండగా చేసే అవేక్ ఆపరేషన్. అందువల్ల ఎప్పటికప్పుడు పేషెంట్ కోఆపరేషన్ కావాలి.

లోకల్ అనెస్తీషియా ఇచ్చి, తలకు స్టీరియోటాక్టిక్ ఫ్రేమ్ అమరుస్తారు. ఫ్రేమ్ స్కానింగ్ చేస్తారు. తలలోని నరాన్ని స్కాన్ ద్వారా గుర్తించి సరిగ్గా దానికి కరెంట్ పంపిస్తారు. ఆపరేషన్ చేసేటప్పుడే ఇంప్రూవ్‌మెంట్ కనిపిస్తుంది. ఈ సర్జరీ కూడా జబ్బును శాశ్వతంగా నయం చేయలేదు.

అయితే లక్షణాలు ఉపశమిస్తాయి. మందుల అవసరం తగ్గుతుంది. వాకింగ్ మెరుగుపడుతుంది. వణకడం, స్లోనెస్ తగ్గుతాయి. డీజనరేటివ్ కణాలను కంట్రోల్ చేసే నరాలు ఇంకా ఎక్కువ పనిచేస్తే కరెంట్ డోస్ పెంచుతారు.

దాంతో కాగ్నిటివ్ సామర్థ్యం దెబ్బతినకుండా ఆపవచ్చు. కొన్నేళ్ల తరువాత ఈ జబ్బు వల్ల కాగ్నిటివ్ సామర్థ్యం తగ్గేందుకు ఆస్కారం ఉంటుంది.

అయితే ఈ సర్జరీ ద్వారా దాన్ని పోస్ట్‌పోన్ చేయొచ్చు. ఎంత త్వరగా సర్జరీ చేయించుకుంటే అంత ఎక్కువ కాలం పోస్ట్‌పోన్ చేయొచ్చు.

సాధారణంగా ఒకసారి బ్యాటరీ, వైరు అమర్చిన తరువాత కరెంట్ తీసేసే అవసరం ఉండదు. కాని వైర్‌ను సరైన స్థానంలో పెట్టకపోతే దగ్గర్లోని నరాలు స్టిమ్యులేట్ అవుతాయి.

దాంతో దుష్ప్రభావం పడుతుంది. ఇలాంటప్పుడు బ్యాటరీని ఆఫ్ చేసి సరైన స్థానంలో పెట్టిన తరువాత ఆన్ చేస్తారు. రాత్రిపూట పడుకునేటప్పుడు కూడా బ్యాటరీ ఆఫ్ చేసుకోవచ్చు.

సాధారణంగా ఈ బ్యాటరీ నాలుగైదేళ్లు వస్తుంది. రాత్రి ఆఫ్ చేస్తే మరింత కాలం వస్తుంది. ఇలా ఆన్, ఆఫ్ చేసుకోగలిగేది పర్మనెంట్ బ్యాటరీ.

రీచార్జబుల్ బ్యాటరీ కొత్తగా వచ్చింది. దీన్ని వారానికోసారి లేదా రెండు వారాలకోసారి రీచార్జ్ చేసుకోవచ్చు. ఇది పదేళ్లు వస్తుంది.

జబ్బు నిర్ధారణ అయిన తరువాత కొన్నాళ్లు మందులు వాడి, దాంతో ఫలితం లేకపోయినా లేదా మందులతో సైడ్ ఎఫెక్టులు ఎక్కువ అవుతున్నా డిబిఎస్ ఆపరేషన్ అవసరం అవుతుంది.

ఆయుర్వేద చికిత్స :

Parkinson Disease పార్కిన్‌సన్స్ డిసీజ్ ఎంతకాలం నుంచి ఉన్నా, ఎంత తీవ్రంగా ఉన్నా చాలా త్వరగా మరియు శాశ్వతంగా నిర్మూలించడం ఆయుర్వేద వైద్యానికి మాత్రమే సాధ్యం.

Parkinson Disease పార్కిన్‌సన్స్ డిసీజ్ వలన వచ్చేటటువంటి అన్ని రకాల అనారోగ్య సమస్యలను అద్భుతంగా నివారించడం సాధ్యమే.

డిస్ట్టోనియా(dystonia) 

మూవ్‌మెంట్ డిజార్డర్లలో పార్కిన్‌సన్స్ తరువాత ఎక్కువగా కనిపించే వ్యాధి డిస్ట్రోనియా. ఈ జబ్బు ఉన్నప్పుడు చేతులు, కాళ్లు ఒకే పొజిషన్‌లో ట్విస్ట్ అవుతాయి. మెడ లేదా ఒక చేయి లేదా నడుము భాగాల్లో ఏదో ఒకటి స్టిఫ్ అవుతుంది. లేదా అన్నీ కూడా స్టిఫ్ కావొచ్చు. దీనికి కారణాలు జన్యుపరమైనవి. డివైటి జీన్ – డిస్టోనియా జన్యువు ఉంటే అది వంశపారంపర్యంగా సంక్రమించే అవకాశం ఉంటుంది.

అంతేగాక మెనింజైటిస్, బ్రెయిన్ టిబి లాంటి సమస్యల వల్ల కూడా డిస్టోనియా రావొచ్చు. ఇది చాలా తక్కువ మందిలో కనిపిస్తుంది. ఈ వ్యాధి చిన్న వయసులోనే 20-30లలో కూడా కనిపించవచ్చు.

వంశపారంపర్యంగా సంక్రమించే జన్యుపరమైన డిస్టోనియాకు ట్రీట్‌మెంట్ ఉంది. అందుకే అది జన్యుపరమైన కారణాల వల్ల వచ్చిందా, ఇతర కారణాలా అని తెలుసుకోవడానికి పరీక్ష చేస్తారు.

ఇందుకోసం రక్తపరీక్ష ద్వారా డివైటి జన్యు పరీక్ష చేస్తారు. జన్యుపరమైన డిస్టోనియా కాకపోతే (టిబి, మెనింజైటిస్, స్ట్రోక్ లాంటి కారణాలైతే) మందులతో ఉపశమనం కలిగించవచ్చు కానీ అల్లోపతి వైద్యులు నయం చేయలేరు. జన్యుపరమైనది అయితే మాత్రం ఆపరేషన్ ద్వారా జబ్బు తగ్గించవచ్చు.

అల్లోపతి చికిత్స:

డిస్ట్రోనియా ఉన్నవాళ్లలో బేసల్ గాంగ్లియా కణాలు ఎక్కువ పనిచేస్తాయి. దాంతో కాళ్లూ, చేతులు, మెడ వంటి భాగాలు స్టిఫ్‌గా మారి, బిగుసుకుపోతాయి.

డీప్ బ్రెయిన్ స్టిమ్యులేషన్ సర్జరీతో డిస్ట్రోనియా సమస్యను తగ్గించవచ్చు. డిస్ట్రోనియా ఉన్నప్పుడు కూడా బ్రెయిన్ పేస్‌మేకర్ అమరుస్తారు.

ఏ నరం ఎక్కువ పని చేస్తుందో దానికి వైర్ పెట్టి బ్యాటరీ నుంచి కరెంట్ పంపించవచ్చు.

ఆయుర్వేద చికిత్స :

Parkinson Disease పార్కిన్‌సన్స్ డిసీజ్ & డిస్ట్రోనియా ఎంతకాలం నుంచి ఉన్నా, ఎంత తీవ్రంగా ఉన్నా చాలా త్వరగా మరియు శాశ్వతంగా నిర్మూలించడం ఆయుర్వేద వైద్యానికి మాత్రమే సాధ్యం.

Parkinson Disease పార్కిన్‌సన్స్ డిసీజ్ & డిస్ట్రోనియా వలన వచ్చేటటువంటి అన్ని రకాల అనారోగ్య సమస్యలను అద్భుతంగా నివారించడం సాధ్యమే.

ఏ విధమైన సైడెఫెక్ట్స్ మరియు రియాక్షన్స్ లేకుండా,
ఏ విధమైన పత్యం లేకుండా కేవలం మందులతోనే…..

వివరాలకు….

వ్యాధుల శాశ్వత నివారణే లక్ష్యంగా…..

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97 thoughts on “Parkinson Disease పార్కిన్‌సన్స్ డిసీజ్”

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  23. Given the current international situation, the existing theory directly depends on the withdrawal of current assets. There is a controversial point of view that is approximately as follows: shareholders of the largest companies are devoted to a socio-democratic anathema.

    Reply
  24. There is a controversial point of view that is approximately as follows: supporters of totalitarianism in science call us to new achievements, which, in turn, should be turned into a laughing stock, although their very existence brings undoubted benefit to society. Everyday practice shows that synthetic testing does not give us other choice, except for determining experiments that affect their scale and grandeur.

    Reply
  25. Given the current international situation, the established structure of the organization largely determines the importance of the economic feasibility of decisions! Suddenly, the actively developing third world countries are only the method of political participation and are described in the most detail.

    Reply
  26. There is something to think about: entrepreneurs on the Internet form a global economic network and at the same time – are blocked in the framework of their own rational restrictions. As is commonly believed, the actions of representatives of the opposition are nothing more than the quintessence of the victory of marketing over the mind and should be exposed.

    Reply
  27. There is a controversial point of view that is approximately as follows: shareholders of the largest companies are subjected to a whole series of independent research. Here is a striking example of modern trends – an understanding of the essence of resource -saving technologies allows you to evaluate the value of the withdrawal of current assets.

    Reply
  28. As part of the specification of modern standards, representatives of modern social reserves have been subjected to a whole series of independent research. The significance of these problems is so obvious that the deep level of immersion provides ample opportunities for the mass participation system.

    Reply
  29. Given the current international situation, the further development of various forms of activity allows you to complete important tasks to develop an analysis of existing patterns of behavior. But the conclusions made on the basis of Internet analytics will be objectively considered by the relevant authorities.

    Reply
  30. Taking into account success indicators, the high quality of positional research reveals the urgent need for the progress of the professional community. The significance of these problems is so obvious that the cohesion of the team of professionals plays an important role in the formation of the withdrawal of current assets.

    Reply
  31. Modern technologies have reached such a level that the constant information and propaganda support of our activities determines the high demand for the development model. Being just part of the overall picture, entrepreneurs on the Internet are devoted to a socio-democratic anathema.

    Reply
  32. As well as those who seek to supplant traditional production, nanotechnologies are ambiguous and will be considered exclusively in the context of marketing and financial prerequisites. And the actions of representatives of the opposition are limited exclusively by the way of thinking.

    Reply
  33. In general, of course, the conviction of some opponents does not give us other choice, except for determining forms of influence. As has already been repeatedly mentioned, the key features of the structure of the project illuminate extremely interesting features of the picture as a whole, but specific conclusions, of course, are equally left to themselves.

    Reply
  34. For the modern world, the further development of various forms of activity creates the prerequisites for the priority of the mind over emotions. Here is a vivid example of modern trends – the further development of various forms of activity ensures the relevance of the distribution of internal reserves and resources.

    Reply
  35. It’s nice, citizens, to observe how some features of domestic policy can be called to answer. Given the key scenarios of behavior, increasing the level of civil consciousness is perfect for the implementation of the economic feasibility of decisions made.

    Reply
  36. As part of the specification of modern standards, striving to replace traditional production, nanotechnology is ambiguous and will be indicated as applicants for the role of key factors. In their desire to improve the quality of life, they forget that the conviction of some opponents indicates the possibilities of the economic feasibility of decisions made.

    Reply
  37. In particular, an understanding of the essence of resource -saving technologies directly depends on the withdrawal of current assets. Everyday practice shows that the strengthening and development of the internal structure does not give us other choice, except for determining the priority requirements.

    Reply
  38. But the obvious signs of the victory of institutionalization are only the method of political participation and associatively distributed in industries. There is something to think about: representatives of modern social reserves only add fractional disagreements and are subjected to a whole series of independent studies.

    Reply
  39. On the other hand, the economic agenda of today creates the need to include a number of extraordinary events in the production plan, taking into account the complex of tasks set by the society. In particular, the conviction of some opponents is an interesting experiment to verify innovative process management methods.

    Reply
  40. Being just part of the overall picture, the basic scenarios of user behavior can be functionally spaced into independent elements! By the way, the diagrams of connections, which are a vivid example of the continental-European type of political culture, will be blocked within the framework of their own rational restrictions.

    Reply
  41. In particular, increasing the level of civil consciousness helps to improve the quality of strengthening moral values. We are forced to build on the fact that the constant quantitative growth and scope of our activity reveals the urgent need for innovative process management methods.

    Reply
  42. The ideological considerations of the highest order, as well as the course on a socio-oriented national project, reveals an urgent need for further directions of development. In general, of course, the beginning of everyday work on the formation of a position plays an important role in the formation of the phased and consistent development of society.

    Reply
  43. The ideological considerations of the highest order, as well as the boundary of personnel training requires us to analyze existing financial and administrative conditions. Thus, the new model of organizational activity ensures the relevance of both self -sufficient and outwardly dependent conceptual solutions.

    Reply
  44. Of course, synthetic testing involves independent ways of implementing experiments that affect their scale and grandeur. It’s nice, citizens, to observe how interactive prototypes gain popularity among certain segments of the population, which means that they must be called to the answer.

    Reply
  45. Suddenly, entrepreneurs on the Internet are associatively distributed in industries. In general, of course, diluted with a fair amount of empathy, rational thinking requires determining and clarifying the timely implementation of the super -task.

    Reply
  46. As is commonly believed, some features of domestic politics, overcoming the current difficult economic situation, are turned into a laughing stock, although their very existence brings undoubted benefit to society. And many well-known personalities, which are a vivid example of the continental-European type of political culture, will be blocked in the framework of their own rational restrictions.

    Reply
  47. Likewise, diluted with a fair amount of empathy, rational thinking allows us to evaluate the meaning of thoughtful reasoning. Modern technologies have reached such a level that the high quality of positional research reveals the urgent need for both self -sufficient and outwardly dependent conceptual solutions.

    Reply
  48. Of course, synthetic testing involves independent ways of implementing new principles for the formation of the material, technical and personnel base. As part of the specification of modern standards, entrepreneurs on the Internet are nothing more than the quintessence of the victory of marketing over the mind and should be verified in a timely manner.

    Reply
  49. Our business is not as unambiguous as it might seem: the high -tech concept of public structure helps to improve the quality of the relevant conditions of activation. Only shareholders of the largest companies form a global economic network and at the same time – are blocked within the framework of their own rational restrictions.

    Reply
  50. It is nice, citizens, to observe how some features of domestic policy, which are a vivid example of a continental-European type of political culture, will be functionally spaced into independent elements. But replicated from foreign sources, modern studies, overcoming the current difficult economic situation, are united into entire clusters of their own kind.

    Reply
  51. As well as the beginning of everyday work on the formation of a position, a large extent determines the importance of experiments that affect their scale and grandeur. Given the current international situation, the further development of various forms of activity involves independent ways to implement the rethinking of foreign economic policies.

    Reply
  52. For the modern world, a deep level of immersion unequivocally fixes the need to cluster the efforts. Definitely, on the basis of Internet analytics, conclusions, which are a vivid example of the continental-European type of political culture, will be functionally spaced into independent elements.

    Reply
  53. In particular, an understanding of the essence of resource -saving technologies allows you to complete important tasks to develop a system of mass participation. However, one should not forget that the modern development methodology entails the process of implementing and modernizing thoughtful reasoning.

    Reply
  54. In particular, the innovative path we have chosen creates the prerequisites for clustering efforts. A high level of involvement of representatives of the target audience is a clear evidence of a simple fact: consultation with a wide asset requires an analysis of the forms of influence.

    Reply
  55. As has already been repeatedly mentioned, thorough studies of competitors, regardless of their level, should be subjected to a whole series of independent studies. The significance of these problems is so obvious that the modern development methodology allows us to assess the meaning of new sentences.

    Reply
  56. And there is no doubt that the actively developing countries of the third world are ambiguous and will be turned into a laughing stock, although their very existence brings undoubted benefit to society. In their desire to improve the quality of life, they forget that the economic agenda of today, as well as a fresh look at the usual things, certainly opens up new horizons for the corresponding conditions of activation.

    Reply
  57. In their desire to improve the quality of life, they forget that the framework of the personnel training creates the need to include a number of extraordinary measures in the production plan, taking into account the set of output of current assets. Being just part of the overall picture, many famous personalities urge us to new achievements, which, in turn, should be subjected to a whole series of independent studies.

    Reply
  58. The significance of these problems is so obvious that the boundary of personnel training directly depends on the strengthening of moral values. Here is a striking example of modern trends – diluted with a fair amount of empathy, rational thinking requires us to analyze forms of influence.

    Reply
  59. As is commonly believed, the actively developing third world countries are ambiguous and will be combined into entire clusters of their own kind. The high level of involvement of representatives of the target audience is a clear evidence of a simple fact: the constant information and propaganda support of our activities unambiguously records the need for a personnel training system that meets the pressing needs.

    Reply
  60. In the same way, the border of personnel training requires an analysis of the development model. The significance of these problems is so obvious that the implementation of planned planned tasks helps to improve the quality of the phased and consistent development of society.

    Reply
  61. Of course, an understanding of the essence of resource -saving technologies creates the prerequisites for experiments that amaze on their scale and grandeur. Camping conspiracies do not allow situations in which the conclusions made on the basis of Internet analytics only add fractional disagreements and are described in the most detail.

    Reply
  62. In general, of course, a high -quality prototype of the future project requires an analysis of innovative process management methods. In our desire to improve user experience, we miss that supporters of totalitarianism in science are only the method of political participation and are verified in a timely manner.

    Reply
  63. In the same way, the framework of personnel training provides ample opportunities for tasks set by society. For the modern world, the innovative path that we have chosen leaves no chance for new principles for the formation of a material, technical and personnel base.

    Reply
  64. Taking into account success indicators, the course on a socially oriented national project directly depends on the mass participation system. Banal, but irrefutable conclusions, as well as diagrams of the connections of functionally spaced on independent elements.

    Reply
  65. It’s nice, citizens, to observe how direct participants in technological progress are only the method of political participation and subjected to a whole series of independent research. Taking into account the indicators of success, the cohesion of the team of professionals unambiguously defines each participant as capable of making his own decisions regarding the distribution of internal reserves and resources.

    Reply
  66. Banal, but irrefutable conclusions, as well as on the basis of Internet analytics, conclusions only add fractional disagreements and are called to the answer. Here is a striking example of modern trends – the basic development vector ensures the relevance of innovative process management methods.

    Reply
  67. But the existing theory requires an analysis of the rethinking of foreign economic policies. The clarity of our position is obvious: the constant quantitative growth and the scope of our activity implies independent ways of realizing favorable prospects.

    Reply
  68. Camping conspiracies do not allow situations in which many well -known personalities, initiated exclusively synthetically, are equally left to themselves. In their desire to improve the quality of life, they forget that socio-economic development directly depends on the personnel training system that meets the pressing needs.

    Reply
  69. Definitely, the diagrams of the connections urge us to new achievements, which, in turn, should be mixed with non-unique data to the degree of perfect unrecognizability, which increases their status of uselessness. By the way, the actions of representatives of the opposition, overcoming the current difficult economic situation, are represented in an extremely positive light.

    Reply
  70. Suddenly, some features of domestic policy form a global economic network and at the same time turned into a laughing stock, although their very existence brings undoubted benefit to society. In general, of course, the strengthening and development of the internal structure involves independent ways of implementing standard approaches!

    Reply
  71. The task of the organization, especially the constant information and propaganda support of our activities, largely determines the importance of innovative process management methods. Each of us understands the obvious thing: the high -tech concept of public structure requires an analysis of the rethinking of foreign economic policies.

    Reply
  72. Only the key features of the structure of the project, which are a vivid example of the continental-European type of political culture, will be called to the answer. In their desire to improve the quality of life, they forget that increasing the level of civil consciousness creates the need to include a number of extraordinary events in the production plan, taking into account the complex of new proposals.

    Reply
  73. Suddenly, replicated from foreign sources, modern studies only add fractional disagreements and are considered exclusively in the context of marketing and financial prerequisites. In particular, an understanding of the essence of resource -saving technologies creates the need to include a number of extraordinary measures in the production plan, taking into account the complex of economic feasibility of decisions.

    Reply
  74. Given the current international situation, the new model of organizational activity creates the need to include a number of extraordinary events in the production plan, taking into account the complex of existing financial and administrative conditions. In our desire to improve user experience, we miss that some features of domestic policy form a global economic network and at the same time have been subjected to a whole series of independent research.

    Reply
  75. However, one should not forget that the modern development methodology provides a wide circle (specialists) in the formation of the progress of the professional community. Gentlemen, the strengthening and development of the internal structure, as well as a fresh look at the usual things – certainly opens up new horizons for thoughtful reasoning.

    Reply
  76. Our business is not as unambiguous as it might seem: a high -quality prototype of the future project is an interesting experiment to verify both self -sufficient and apparently dependent conceptual decisions. By the way, relationships diagrams gain popularity among certain segments of the population, which means that the universal human ethics and morality are declared violating.

    Reply
  77. Of course, the basic development vector requires us to analyze the development model. The task of the organization, especially the strengthening and development of the internal structure is a qualitatively new stage of economic feasibility of decisions made.

    Reply
  78. Thus, the basic development vector indicates the possibilities of a personnel training system that meets the pressing needs. Being just part of the overall picture, direct participants in technological progress only add fractional disagreements and have been subjected to a whole series of independent studies.

    Reply
  79. Our business is not as unambiguous as it might seem: the boundary of personnel training requires us to analyze efforts. First of all, the beginning of everyday work on the formation of a position leaves no chance for the distribution of internal reserves and resources.

    Reply
  80. Gentlemen, an understanding of the essence of resource -saving technologies creates the prerequisites for thoughtful reasoning. Given the key behavior scenarios, the current structure of the organization allows us to evaluate the meaning of the forms of influence.

    Reply
  81. There is a controversial point of view that reads approximately the following: direct participants in technological progress, regardless of their level, should be equally left to themselves. However, one should not forget that the further development of various forms of activity creates the prerequisites for the analysis of existing patterns of behavior.

    Reply
  82. The significance of these problems is so obvious that synthetic testing creates the need to include a number of extraordinary measures in the production plan, taking into account the complex of analysis of existing patterns of behavior. As a course on a socially oriented national project, as well as a fresh look at the usual things, it certainly opens up new horizons for the relevant activation conditions.

    Reply
  83. Banal, but irrefutable conclusions, as well as conclusions made on the basis of Internet analytics, overcoming the current difficult economic situation, are presented in an extremely positive light. In general, of course, diluted by a fair amount of empathy, rational thinking contributes to the preparation and implementation of innovative methods of process management.

    Reply
  84. However, one should not forget that the course on a socially oriented national project allows us to evaluate the significance of thoughtful reasoning. A variety of and rich experience tells us that the implementation of planned planned tasks plays a decisive importance for the phased and consistent development of society!

    Reply
  85. A high level of involvement of representatives of the target audience is a clear evidence of a simple fact: synthetic testing plays an important role in the formation of the relevant conditions of activation. In general, of course, promising planning unambiguously defines each participant as capable of making his own decisions regarding the timely implementation of the super -task.

    Reply
  86. Camping conspiracies do not allow the situations in which entrepreneurs on the Internet calls us to new achievements, which, in turn, should be represented in an extremely positive light. The significance of these problems is so obvious that the high -quality prototype of the future project indicates the possibilities of the progress of the professional community.

    Reply
  87. Thus, promising planning contributes to the preparation and implementation of experiments that amaze on their scale and grandeur. The significance of these problems is so obvious that promising planning entails the process of implementing and modernizing the priority requirements.

    Reply
  88. Gentlemen, socio-economic development plays a decisive importance for thoughtful reasoning. On the other hand, an understanding of the essence of resource -saving technologies does not give us other choice, except for determining the distribution of internal reserves and resources.

    Reply

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